Courses
Courses for Kids
Free study material
Offline Centres
More
Store Icon
Store

Cholera Overview Causes Symptoms and Prevention

share icon
share icon
banner

What Is Cholera Definition Transmission Pathogenesis and Treatment

When the normal human body condition deteriorates, then the condition is known as disease. Each disease has its own signs and symptoms. It can also be defined as a divergence of human body condition from its normal state. Example: when a person comes in contact with any kind of harmful pathogen, then in that case they show certain symptoms depending on body condition, which may be called a disease. Hence, in order to know about which kind of disease we are suffering through, we have to study all types of diseases. It's not necessary that a disease will show only a single symptom as it can show many symptoms also depending upon variation of the disease. Some of the very common symptoms of diseases are headaches, cough, cold, weakness. 


Types of Diseases:

Diseases are categorised into two types, they are:

A. Infectious Disease: 

It is a kind of disease that can be transmitted from one person to another, and due to this reason they are called communicable diseases. Such diseases are mainly caused by microorganisms, which are termed as pathogens like: (fungi, rickettsia, bacteria, viruses, protozoans, worms). When a fluid of an infected person is discharged then at that time pathogens may leave the host and infect a new person's body. Body fluid is discharged by processes like sneezing, coughing etc. Examples of infectious disease are Cholera, chickenpox, malaria etc.

B. Non-infectious Disease: 

In this type of disease, people get infected by pathogens, but along with that other factors also play a role: age, nutritional deficiency, the gender of an individual, and lifestyle also influence the disease. Examples of non-infectious diseases are hypertension, diabetes, and cancer. As this disease cannot be transferred from one person to another so it remains inside the single person only. 


Classification of Diseases on the Basis of Duration:

Based on duration, diseases can be categorised into two types:

A. Acute Disease:  It is a kind of disease which occurs only for a short interval of time. An acute disease, if not treated properly, can eventually become a chronic disease. e.g. common cold, burn, etc.

B. Chronic Disease: It is a kind of disease which lasts for a long duration of time. Some of the common examples of this disease are heart and kidney diseases.

Cholera:

It is a kind of bacterial disease which is mainly caused by the bacterium Vibrio cholerae. We can get this bacteria mainly in contaminated foods and water. It is also present in areas where there are no proper sanitation facilities. Discovery of this disease took place in the US during the 1800s and it caused major health problems to people for hundreds of years. Some of the commonly known symptoms of this disease are severe diarrhoea and leading to dehydration in the body and sometimes it might lead to a fatal condition.


About Cholera Bacteria:

The scientific name of cholera bacteria is Vibrio cholerae, it is mainly curved and comma-shaped and is gram-negative bacteria. It is mostly found in coastal saltwater areas and in the sewage. They attach themselves to the shells of shell-fish, crabs, etc. When we drink contaminated water it causes various threatening diseases and one among them is cholera.

They live in the small intestine of the human body and release an exotoxin that causes a flow of water and certain electrolytes such as the sodium bicarbonate, chloride etc, into the small intestine.


Symptoms of Cholera:

Some of the common symptoms of cholera are discussed below:

A. High fever.

B. Lead to increased thirst.

C. Sudden weight loss.

D. Decrease in blood pressure.

E. Feeling of Nausea

F. Formation of blood or mucus or sometimes undigested materials in the stool.

G. A kind bloating in the belly.

H. decrease in elasticity of the skin.

I. Causes cramps in the muscles.

J. Dryness in the mouth, nose, and eyelids.

K. Vomiting sensation

L. A sudden increase in the heart rate.

Causes of Cholera:

Some of the common causes of cholera are discussed below: 

A. It can be caused by various factors like contaminated water supply or by drinking contaminated water. 

B. It can also be caused by consumption of contaminated foods and drinks like street food. 

C. Vegetables can also cause cholera-like the vegetables which are grown with the use of water with human wastes.

D. By eating contaminated sea-foods, which are polluted with sewage.

E. It can also be caused by the consumption of foods that affect the functioning of the digestive system.

Preventative Measures:

Some of the precautions which we can take to protect us from cholera are discussed below:

A. By drinking boiled water.

B. By avoiding consumption of raw foods.

C. By avoiding dairy products as much as you can.

D. By washing fruits and vegetables before you eat or use them for cooking purposes.

E. Washing your hands properly before you eat is the easiest way to protect yourself from the disease.

F. Drink plenty of water and it is recommended to drink about 8 ounces of water every day.

Want to read offline? download full PDF here
Download full PDF
Is this page helpful?
like-imagedislike-image

FAQs on Cholera Overview Causes Symptoms and Prevention

1. What is cholera?

Cholera is an acute diarrheal disease caused by infection of the small intestine with the bacterium Vibrio cholerae. It spreads mainly through contaminated water and food and leads to severe watery diarrhea and dehydration.

  • Caused by Vibrio cholerae, a comma-shaped Gram-negative bacterium
  • Affects the small intestine
  • Can become life-threatening if dehydration is not treated promptly

2. What causes cholera infection?

Cholera infection is caused by ingestion of water or food contaminated with Vibrio cholerae. The bacteria multiply in the intestine and release toxins that trigger severe diarrhea.

  • Common in areas with poor sanitation and unsafe drinking water
  • Spread through contaminated seafood, raw foods, and unclean water
  • Outbreaks often occur after floods or in crowded settings

3. How does Vibrio cholerae cause diarrhea?

Vibrio cholerae causes diarrhea by producing cholera toxin, which increases water and electrolyte secretion in the intestine. The toxin activates adenylate cyclase in intestinal cells, raising cyclic AMP levels and causing massive fluid loss.

  • Cholera toxin binds to intestinal epithelial cells
  • Increases cAMP levels inside cells
  • Leads to secretion of chloride ions and water into the intestinal lumen

4. What are the main symptoms of cholera?

The main symptoms of cholera are profuse watery diarrhea, vomiting, and rapid dehydration. The stool is often described as “rice-water” in appearance.

  • Severe watery diarrhea
  • Vomiting and muscle cramps
  • Signs of dehydration such as dry mouth, low blood pressure, and sunken eyes

5. How is cholera transmitted?

Cholera is transmitted primarily through the fecal–oral route via contaminated water and food. Poor hygiene and inadequate sanitation systems increase transmission risk.

  • Drinking contaminated water
  • Eating improperly cooked seafood
  • Consumption of food handled with unwashed hands

6. What is cholera toxin and how does it work?

Cholera toxin is a protein exotoxin produced by Vibrio cholerae that disrupts ion transport in intestinal cells. It consists of A and B subunits that enter epithelial cells and stimulate excessive fluid secretion.

  • B subunit binds to intestinal cell receptors
  • A subunit activates adenylate cyclase
  • Causes loss of water and electrolytes into the intestine

7. How is cholera treated?

Cholera is treated mainly with rapid rehydration using oral rehydration solution (ORS) or intravenous fluids in severe cases. Early treatment can reduce mortality significantly.

  • ORS replaces lost fluids and electrolytes
  • Severe cases require intravenous saline
  • Antibiotics may shorten the duration of illness

8. How can cholera be prevented?

Cholera can be prevented through safe water, proper sanitation, hygiene practices, and vaccination. Public health measures are key in controlling outbreaks.

  • Drinking boiled or treated water
  • Proper sewage disposal and sanitation
  • Use of oral cholera vaccines in high-risk areas

9. What is the difference between cholera and other types of diarrhea?

Cholera differs from other types of diarrhea because it causes extremely large volumes of watery stool due to the action of cholera toxin. Unlike many infections, it usually does not cause blood or pus in the stool.

  • Produces “rice-water” stools
  • Rapid and severe dehydration
  • Typically no intestinal tissue invasion

10. Why is cholera considered life-threatening?

Cholera is considered life-threatening because it can cause rapid and severe dehydration leading to shock and death if untreated. Massive fluid loss may occur within hours.

  • Loss of water and electrolytes
  • Risk of hypovolemic shock
  • High mortality without prompt rehydration therapy