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What Is a Nephron and How Does It Work?

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Structure and Functions of the Nephron in the Human Kidney

The nephron is the essential structural and functional unit of the kidney, playing a crucial role in filtering blood and forming urine. Every human kidney contains around a million nephrons, working tirelessly to maintain fluid balance, remove waste, and regulate essential substances. Understanding the nephron helps us appreciate how the body controls water, salts, and toxins, supporting overall health and homeostasis.


What is Nephron?

Nephrons are microscopic tubular structures within the kidney that filter blood and produce urine. Each nephron operates independently, performing vital processes that remove unwanted substances and maintain stability in the body's internal environment. If you’ve ever wondered how the kidney “cleans” your blood, the answer lies in the amazing function of each nephron.


Nephron Structure

The structure of a nephron is divided into several major parts, each with a unique function. Let's explore the main regions that make up the nephron structure and see how they work together for efficient filtration.


Labelled Nephron Diagram

Parts of a Nephron

  • Bowman’s Capsule: A cup-shaped structure that surrounds the glomerulus and collects the filtrate from blood.
  • Glomerulus: A cluster of tiny capillaries where blood filtration begins. Learn more about the glomerulus.
  • Proximal Convoluted Tubule (PCT): Reabsorbs water, glucose, and salts back into the blood.
  • Loop of Henle: Extends into the kidney medulla; helps in concentrating urine by reabsorbing water and salts.
  • Distal Convoluted Tubule (DCT): Regulates sodium, potassium, and pH; further adjusts urine composition.
  • Collecting Duct: Collects urine from multiple nephrons, delivering it to the renal pelvis for excretion.

This arrangement ensures efficient filtration, reabsorption, and secretion. Understanding the structure of nephron (nephron diagram class 10, labelled nephron diagram) provides insight into how kidneys function in our daily lives.


Nephron Diagram (Simple & Class 10)

A labelled diagram of nephron is essential for visualizing how each part works. Students often draw a simple diagram of nephron with the glomerulus, tubules, and collecting ducts clearly marked. Practice nephron drawing regularly for exams.


Types of Nephron

There are two main types of nephrons in the human kidney. Each type has unique features and functional roles that contribute to the kidneys’ ability to process vast amounts of blood every day.


  • Cortical Nephron: Found mostly in the outer cortex, these nephrons have shorter loops of Henle and are involved in filtration and reabsorption.
  • Juxtamedullary Nephron: Located near the boundary of the cortex and medulla, with long loops of Henle; crucial for producing concentrated urine.

The difference between these nephron types highlights their specialized roles in water conservation and salt regulation, essential for survival when water is scarce.


Structure of Nephron: Detailed Explanation

Let’s describe the structure and functioning of nephron step by step. This is especially important for students in class 10 who are expected to explain the structure of nephron for their board exams.


  1. Blood enters the nephron through the glomerulus, where filtration occurs in the Bowman’s capsule.
  2. PCT reabsorbs useful solutes and water, returning them to the bloodstream.
  3. Loop of Henle creates a concentration gradient in the kidney medulla, crucial for water reabsorption.
  4. DCT further regulates ions and pH, using hormones like aldosterone for balance.
  5. Collecting Duct fine-tunes water content in urine, influenced by antidiuretic hormone (ADH).

Each region of the nephron structure is specialized for functions like reabsorption, secretion, or urine concentration, making the nephron far more than just a simple filter!


Function of Nephron

What is the function of nephron? Primarily, nephrons maintain the body’s internal environment. They remove waste, regulate blood pressure, and control the volume and concentration of body fluids. Let’s break down the key functions of nephron for class 10 and advanced learners:


  • Filtration: Removes waste and excess substances from the blood.
  • Reabsorption: Returns useful molecules and water to the bloodstream.
  • Secretion: Transfers additional waste products from blood into the nephron tubule.
  • Urine Formation: Produces urine, which collects in the collecting duct and drains from the kidney.
  • Homeostasis: Maintains balance of salt, water, and pH in the body.

The function of nephron ensures toxic substances do not accumulate and that the body retains essential nutrients and water—a process vital to our health.


Nephron in Kidney: Real-World Importance

Nephrons in kidneys are vital for human health. A failure in nephron function can lead to kidney disorders, affecting the body’s balance. Medicine, agriculture, and even environmental studies relate to nephron efficiency and kidney health. Measurement of substances like urea or proteins in urine can indicate nephron health—a key aspect of diagnosing diseases. Refer to related topics like the human excretory system, dialysis, and kidney disorders for more information.


Differences: Alveoli vs Nephron

FeatureAlveoliNephron
OrganLungsKidney
Main FunctionGas exchange (Oxygen/CO₂)Filtration and urine formation
StructureAir sacsTubular unit

While both are specialized structures, alveoli exchange gases, and nephrons manage fluid and waste through urine formation.


Quick Recap: Structure and Function of Nephron

To describe the structure and function of nephron quickly: the nephron includes the glomerulus, tubules, and collecting duct. It filters blood, reabsorbs useful substances, secretes waste, and creates urine. Without the nephron's function, our bodies could not maintain chemical and fluid balance or excrete toxins effectively.


Explore More with Vedantu

Understanding the nephron not only prepares you for exams but also explains essential physiological processes. For deeper insights into biological topics, check out resources on biomolecules, animal adaptations, and genetics. Vedantu provides easy, student-friendly notes, diagrams, and expert guidance to help you master challenging concepts.


The nephron is the cornerstone of kidney function and body fluid regulation. Knowing its structure and roles helps us comprehend health, disease, and the science behind urine formation. By mastering nephron concepts, you build a solid foundation in human physiology and prepare yourself for advanced biology topics and real-life applications.

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FAQs on What Is a Nephron and How Does It Work?

1. What is a nephron and what is its function in the kidney?

A nephron is the structural and functional unit of the kidney responsible for urine formation and regulation of substances in the blood.

Key functions include:

  • Filtration: Removes waste and excess molecules from blood
  • Reabsorption: Recovers essential nutrients and water
  • Secretion: Transfers additional waste into the filtrate
  • Excretion: Produces urine for elimination

2. What are the main parts of a nephron?

The main parts of a nephron are specialized for filtration, absorption, and secretion of blood components.

Main parts include:

  1. Bowman's capsule
  2. Glomerulus
  3. Proximal convoluted tubule (PCT)
  4. Loop of Henle (descending and ascending limbs)
  5. Distal convoluted tubule (DCT)
  6. Collecting duct

3. How does urine formation take place in the nephron?

Urine formation in the nephron involves filtration, reabsorption, secretion, and concentration of waste.

The main steps are:

  • Glomerular filtration: Blood is filtered in the glomerulus
  • Tubular reabsorption: Useful substances like glucose and amino acids are reabsorbed
  • Tubular secretion: Additional waste (ions, drugs) is secreted into tubules
  • Concentration: Water is adjusted and urine is concentrated in the collecting duct

4. How many nephrons are found in each kidney?

Each human kidney contains approximately 1 to 1.5 million nephrons, which function together to purify blood and form urine efficiently.

5. What is the role of the glomerulus in the nephron?

The glomerulus is responsible for ultrafiltration of blood, where water, ions, and small molecules are filtered out while retaining blood cells and proteins.

  • Located inside Bowman's capsule
  • Initiates urine formation
  • Key for selective permeability

6. What are the types of nephrons and how do they differ?

There are two main types of nephrons in the kidney with distinct functions:

  • Cortical nephrons: Located mainly in the cortex, shorter loop of Henle, help in major filtration
  • Juxtamedullary nephrons: Extend deep into medulla, with long loop of Henle, important for concentration of urine

7. What is the function of the loop of Henle in the nephron?

The loop of Henle plays a crucial role in concentrating urine by creating a concentration gradient in the kidney medulla.

  • Descending limb: Permeable to water, helps in water reabsorption
  • Ascending limb: Permeable to salts, helps in active transport of sodium and chloride ions

8. How does the nephron maintain homeostasis in the human body?

The nephron maintains homeostasis by regulating the balance of water, electrolytes, and pH in the blood.

  • Removes metabolic wastes
  • Regulates blood volume
  • Controls levels of sodium, potassium, and other ions
  • Maintains acid-base balance

9. What is the difference between filtration and reabsorption in the nephron?

Filtration in the nephron is the process where blood plasma is filtered to form filtrate; reabsorption is where useful substances are taken back into blood.

  • Filtration: Takes place in glomerulus; non-selective
  • Reabsorption: Takes place in PCT, loop of Henle, DCT; selective for needed substances

10. What happens if the nephrons in the kidneys are damaged?

Damage to nephrons can severely affect kidney function, leading to accumulation of waste in the body.

  • May result in kidney failure or chronic kidney disease
  • Waste and toxic substances accumulate in the blood
  • Necessary dialysis or kidney transplant may be required in severe cases

11. Where is the nephron located in the human kidney?

A nephron is located within both the cortex and medulla of the human kidney, allowing for filtration, absorption, and urine concentration.

12. Why is the nephron called the functional unit of the kidney?

The nephron is referred to as the functional unit of the kidney because it performs all the essential physiological processes needed for blood purification and urine formation, such as filtration, reabsorption, and secretion.